The results of experimental studies in earthquake resistance of «HARPOON» self-drilling bolt screws (GLOBAL RIVET Company) under dynamic load are set forth. In the course of the tests using a two-component vibroplatform the dynamic effects were modeled in the form of the cyclic (harmonic) load, impulse input (seismic impact) and repeated transient load. Basing on the test results, the recommendations are given on using «HARPOON” fastening elements to connect cladding sandwich panels to steel frames of buildings to be erected in areas with 7-9 point seismicity.